First Quantum-Enhanced Images of a Living Cell / at a resolution of 10 nanometres

 Today, Michael Taylor at the University of Queensland in Australia and a few pals reveal a new way to create optical images of cells that dramatically increases their resolution beyond the conventional diffraction limit. Their trick relies on a peculiar quantum phenomenon called “squeezed light” which has allowed them to resolve spatial  structures inside a living cells at a resolution of 10 nanometres; that’s a 14 per cent finer resolution than is possible with conventional techniques.

 

First Quantum-Enhanced Images of a Living Cell | MIT Technology Review.

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The only innovation that matters

There is no medicine less useful to the world or its maker than one that does not make it to market in robust health. That is why we measure Productive Innovation – it is the only measure of innovation in the pharma industry that matters. Pipelines full of products that fail to get to market or fail once on market may contribute to the management consultancies’ ‘productivity’ numbers, but they matter not one jot in the real world.

via The only innovation that matters.

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In the footsteps of Schrödinger: understanding the physics of life

 

During malarial infection, parasites multiply within red blood cells and then egress to adhere and infect new red blood cells. This optical microscope image shows (false colours) a cluster of parasites (yellow) just released, and about to infect neighbouring cells (red). Photograph: A. Crick and P. Cicuta

Erwin Schrödinger, the Austrian physicist whose eponymous equation lies at the heart of quantum mechanics, strayed beyond his normal disciplinary boundaries when he wrote a book called The Physics of Life in 1944. He was bringing concepts from physics – notably statistical physics – to bear on the complex behaviour of living organisms.

In the footsteps of Schrödinger: understanding the physics of life | Athene Donald | Science | guardian.co.uk.

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Which next innovation is disruptive for the pharmaceutical industry?

A lot is written about innovation in the pharmaceutical industry at the moment, there is a huge momentum generated by the “Open Innovation” initiative. Whatever kind of innovation is discussed, it is clear that innovation in the pharmaceutical environment is needed.

Post by Bernd Muehlenweg, PhD

It is needed to bring new treatments to patients, not only for rare diseases, also safer and more efficacious substitutions for existing treatments are needed.
It is needed for the pharmaceutical companies to prevent a reduction in revenues due to the “patent cliff” they will meet over the next couple of years. If pharma companies do not care about innovation they will not be able to sustain their business and infrastructure.

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Nanomedicine article: nanoXRay for cancer therapy published in future oncology

NanoXray is a nanomedicine technology: a new solution addressing current limitations of radiotherapy

The local treatment of malignant tumors is the cornerstone of cancer treatment, for which standard treatments are surgery and radiotherapy, either used independently or in combination. Radiotherapy has been widely used in most oncology indications for decades. About 60% of cancer patients receive radiotherapy at some point of their treatment regime.

Today, many cancer patients do not receive doses sufficient for tumor destruction, respond insufficiently or not at all to treatments, or even develop resistance to these treatments. In order to obtain greater radiotherapy efficacy, the dose delivered to the tumor must be increased without increasing its effect on healthy tissues.

The fundamental goal of Nanoxray is to provide a solution to the question of “how to increase the delivered dose to the tumor without increasing it in healthy tissue?”This will lead to a greatly improved efficacy of radiotherapy and most likely increase the overall efficacy of cancer treatment.

This online article published in future oncology establishes the bases for NanoXray technology.

Article from Future Medicine in PDF

 

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